Description

n-(tert-Butoxycarbonyl)-1 H-Pyrazole-1-Carboxamidine is a specialized Boc-protected carboxamidine reagent, a high-purity building block of significant value in advanced organic synthesis. Its primary importance lies in its role as a versatile precursor for introducing the amidine functional group under mild conditions, which is critical for constructing heterocyclic scaffolds and pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality reagents for complex molecule assembly.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the preparation of nitrogen-containing heterocycles, such as pyrazoles and fused pyrazole derivatives, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in the synthesis of novel compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Peptidomimetics & Bioactive Molecule Design: Serves as a reagent for the modification of peptides and the creation of amidine-based bioisosteres to enhance drug-like properties.
• Material Science Chemistry: Employed in the synthesis of specialized ligands, catalysts, and organic frameworks where precise nitrogen integration is required.
• Academic & Contract Research: A valuable tool for methodological development in organic synthesis and for exploring new chemical spaces in academic and industrial R&D laboratories.

Basic Information

Product Name	n-(tert-Butoxycarbonyl)-1 H-Pyrazole-1-Carboxamidine
CAS No.	152120-61-1
Molecular Formula	C9H14N4O2
Molecular Weight	210.24 g/mol
Synonyms	1H-Pyrazole-1-carboximidamide, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl N-(1H-pyrazol-1-ylcarboximidoyl)carbamate; Boc-Pyrazole-Carboxamidine; (tert-Butoxycarbonyl)pyrazole-1-carboxamidine; 1-(N-Boc-carbamimidoyl)-1H-pyrazole; N-Boc-1H-pyrazole-1-carboxamidine; Pyrazole-1-carboxamidine, N-Boc-protected; N-(tert-Butoxycarbonyl)pyrazole-1-carboxamidine
EINECS	Contact for details

Quality Control

Our n-(tert-Butoxycarbonyl)-1 H-Pyrazole-1-Carboxamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reproducible results in sensitive synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.