Description

Methanesulfonic Acid, 1,1,1-Trifluoro-, 4-Oxo-4H-1-Benzopyran-7-Yl Ester is a specialized fluorinated methanesulfonate ester derivative, serving as a high-value synthetic intermediate and building block in advanced organic chemistry. Its molecular architecture, combining a trifluoromethanesulfonyl (triflyl) group with a chromone (benzopyran) moiety, makes it a critical reagent for introducing specific functionalities under controlled conditions. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, including potential active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring the chromone scaffold or triflate leaving groups for cross-coupling reactions.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the fluorinated ester group can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or precursor for specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Organic Synthesis Reagent: Acts as a versatile triflating agent for converting phenols into aryl triflates, which are pivotal intermediates in palladium-catalyzed reactions like Suzuki and Stille couplings.
• Chemical Biology Probe Development: Utilized in creating fluorescent probes or activity-based protein profiling agents due to the chromone fluorophore and reactive ester functionality.

Basic Information

Item	Details
Product Name	Methanesulfonic Acid, 1,1,1-Trifluoro-, 4-Oxo-4H-1-Benzopyran-7-Yl Ester
CAS No.	151895-74-8
Molecular Formula	C11H5F3O5S
Molecular Weight	306.22 g/mol
Synonyms	7-Hydroxy-4-oxo-4H-chromen-2-yl trifluoromethanesulfonate; 7-Trifluoromethanesulfonyloxy-4H-chromen-4-one; Chromone-7-yl triflate; 4-Oxo-4H-chromen-7-yl trifluoromethanesulfonate; 7-(Trifluoromethanesulfonyloxy)-4H-chromen-4-one; Trifluoromethanesulfonic acid 4-oxo-4H-chromen-7-yl ester; 7-Triflyloxychromone
EINECS	Contact for details

Quality Control

Every batch of Methanesulfonic Acid, 1,1,1-Trifluoro-, 4-Oxo-4H-1-Benzopyran-7-Yl Ester is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard analytical suite includes HPLC for purity determination, NMR for structural confirmation, and Karl Fischer titration for moisture content. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.