Description

4-Hydroxy-6-Methyl-3-[2-(4-Phenyl-1,3-Thiazol-2-Yl)Ethanehydrazonoyl]-2H-Pyran-2-One CAS NO 151504-48-2 is a specialized heterocyclic organic compound featuring a unique molecular architecture combining pyran-2-one and thiazole moieties. This structure makes it a valuable advanced intermediate for research and development in pharmaceutical chemistry and agrochemical synthesis. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for lead optimization.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting specific enzymatic pathways.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or insecticides with unique modes of action.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study biological processes and protein interactions.
• Material Science Research: Potential precursor for organic electronic materials or specialty polymers due to its conjugated system.
• Academic & Institutional R&D: Fundamental research compound for studying heterocyclic chemistry reactions and synthesis methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules in multi-step syntheses.

Basic Information

Product Name	4-Hydroxy-6-Methyl-3-[2-(4-Phenyl-1,3-Thiazol-2-Yl)Ethanehydrazonoyl]-2H-Pyran-2-One
CAS No.	151504-48-2
Molecular Formula	C₁₈H₁₅N₃O₃S
Molecular Weight	353.40 g/mol
Synonyms	3-[(2-(4-Phenyl-1,3-thiazol-2-yl)ethylidene)hydrazinylidene]-4-hydroxy-6-methyl-2H-pyran-2-one; 4-Hydroxy-6-methyl-3-[(2-(4-phenyl-1,3-thiazol-2-yl)ethylidene)hydrazono]-2H-pyran-2-one; 2H-Pyran-2-one, 4-hydroxy-6-methyl-3-[2-(4-phenyl-2-thiazolyl)ethylydene]hydrazone; CAS 151504-48-2; 4-Hydroxy-6-methyl-3-[2-(4-phenylthiazol-2-yl)ethylidenehydrazono]pyran-2-one; 151504-48-2
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.