Description

3-Chloro-2-(Trifluoromethoxy)Aniline is a specialized aromatic amine derivative, distinguished by the presence of both chloro and trifluoromethoxy substituents. This unique molecular structure makes it a valuable and versatile chemical intermediate for synthesizing advanced compounds with tailored properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of active pharmaceutical ingredients (APIs) with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental profile.
• Material Science Research: Serves as a precursor for functional dyes, liquid crystals, and other advanced organic materials requiring specific electronic properties.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex nitrogen-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and fine chemical production under cGMP or ISO standards.

Basic Information

Product Name	3-Chloro-2-(Trifluoromethoxy)Aniline
CAS No.	151276-16-3
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	3-Chloro-2-(trifluoromethoxy)benzenamine; 2-Amino-6-chloro-α,α,α-trifluoroanisole; 3-Chloro-α,α,α-trifluoro-o-anisidine; 3-Chloro-2-(trifluoromethoxy)phenylamine; Benzenamine, 3-chloro-2-(trifluoromethoxy)-; 2-Trifluoromethoxy-3-chloroaniline
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Trifluoromethoxy)Aniline is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.