Description

1-(4-Bromomethyl-Benzenesulfonyl)-Pyrrolidine is a specialized organic building block featuring a reactive bromomethyl group and a sulfonamide moiety. This compound matters as a versatile intermediate for constructing complex molecules, particularly in medicinal chemistry and materials science. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel sulfonamide-based active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides containing the benzenesulfonyl group.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for introducing sulfonamide and bromo-reactive sites into polymer chains.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes and affinity labels for studying protein function.
• Ligand and Catalyst Development: Building block for creating novel ligands for metal catalysis or organocatalysts.
• Custom Synthesis and R&D: A critical starting material for contract research organizations (CROs) and academic labs exploring new chemical entities.

Basic Information

Product Name	1-(4-Bromomethyl-Benzenesulfonyl)-Pyrrolidine
CAS No.	151258-20-7
Molecular Formula	C11H14BrNO2S
Molecular Weight	304.20 g/mol
Synonyms	4-(Bromomethyl)-N-(pyrrolidin-1-yl)benzenesulfonamide; 1-[(4-Bromomethyl)phenylsulfonyl]pyrrolidine; N-(Pyrrolidin-1-yl)-4-(bromomethyl)benzenesulfonamide; 4-(Bromomethyl)benzenesulfonylpyrrolidine; Pyrrolidine, 1-[(4-bromomethyl)benzenesulfonyl]-; 1-(4-Bromomethylphenylsulfonyl)pyrrolidine; Benzenesulfonamide, 4-(bromomethyl)-N-1-pyrrolidinyl-
EINECS	Contact for details

Quality Control

Our 1-(4-Bromomethyl-Benzenesulfonyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.