Description

5-Bromo-2-Thienylzinc Bromide is a highly reactive organozinc reagent, specifically a thienylzinc halide, widely utilized in modern synthetic chemistry. Its core value lies in enabling efficient, selective cross-coupling reactions, such as Negishi coupling, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable building block for introducing the 5-bromothiophene moiety into target molecules.

Application

• Pharmaceutical Intermediates: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing functionalized thiophene rings.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that incorporate halogenated heterocycles.
• Material Science: Employed in the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials for electronic devices.
• Negishi Cross-Coupling Reactions: Serves as a superior organometallic partner for coupling with various aryl, heteroaryl, and vinyl halides under mild conditions.
• Ligand and Catalyst Development: Useful for preparing novel ligands and organometallic catalysts with tailored electronic properties.
• Fine Chemical and Dye Manufacturing: Facilitates the synthesis of complex dyes, pigments, and specialty fine chemicals.

Basic Information

Product Name	5-Bromo-2-Thienylzinc Bromide
CAS No.	151073-94-8
Molecular Formula	C4H2Br2SZn
Molecular Weight	304.33 g/mol
Synonyms	2-Bromo-5-thienylzinc bromide; (5-Bromothiophen-2-yl)zinc bromide; Zinc, bromo(5-bromo-2-thienyl)-; 5-Bromo-2-thienylzinc bromide solution; 5-Bromothiophene-2-zinc bromide; Thienylzinc bromide, 5-bromo-; Bromo(5-bromo-2-thienyl)zinc
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Thienylzinc Bromide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for zinc content and GC/HPLC analysis for purity and solvent composition, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, concentration, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. Keep away from heat, sparks, open flames, and strong oxidizing agents. Due to its highly volatile and moisture-sensitive nature, the reagent should be handled and transferred under anhydrous conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (Typical)
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms
Solvent Content (GC)	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.