Description

Cyclobutanecarboxylic Acid, 2,3-Bis(Hydroxymethyl)- (9Ci) is a high-purity, functionalized cyclobutane derivative characterized by its carboxylic acid and dual hydroxymethyl groups. This unique bifunctional structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Serves as a precursor for creating new herbicides and fungicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to synthesize complex chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored thermal and mechanical properties.
• Academic & Industrial Research: A valuable tool in medicinal chemistry and material science research for exploring structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2,3-Bis(Hydroxymethyl)- (9Ci)
CAS No.	150521-41-8
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	2,3-Bis(hydroxymethyl)cyclobutanecarboxylic acid; (1R,2S)-rel-2,3-Bis(hydroxymethyl)cyclobutanecarboxylic Acid; Cyclobutane-1-carboxylic acid, 2,3-bis(hydroxymethyl)-; 2,3-Di(hydroxymethyl)cyclobutanecarboxylic acid; Bifunctional Cyclobutane Derivative
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2,3-Bis(Hydroxymethyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and GC to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.