Description

3-Fluoro-5-(Trifluoromethyl)Benzylamine is a high-value fluorinated aromatic amine building block, essential for introducing specific steric and electronic properties into advanced molecular architectures. Its unique structure, featuring both fluorine and trifluoromethyl substituents, makes it a critical intermediate for modulating the lipophilicity, metabolic stability, and binding affinity of target compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine motifs enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science: Incorporated into monomers for the production of specialty polymers with tailored surface properties and chemical resistance.
• Liquid Crystal and OLED Materials: Utilized in the synthesis of fluorinated components for electronic display technologies.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers serving diverse R&D needs.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Benzylamine
CAS No.	150517-77-4
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	[3-Fluoro-5-(trifluoromethyl)phenyl]methanamine; 1-(Aminomethyl)-3-fluoro-5-(trifluoromethyl)benzene; α-Amino-3-fluoro-5-(trifluoromethyl)toluene; 3-Fluoro-5-trifluoromethylbenzylamine; 3-Fluoro-α-(trifluoromethyl)benzylamine; (3-Fluoro-5-(trifluoromethyl)phenyl)methanamine; Benzenemethanamine, 3-fluoro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for advanced applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong bases and should be kept away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.