Description

4-Bromo-2-(Bromomethyl)-1-Chlorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring three distinct halogen substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated benzyl or aryl motifs.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its halogen atoms can be further functionalized.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers and advanced organic materials.
• Chemical Library Building: A valuable scaffold for generating diverse compound libraries in medicinal chemistry and high-throughput screening programs.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex halogenated dyes and organic pigments.

Basic Information

Product Name	4-Bromo-2-(Bromomethyl)-1-Chlorobenzene
CAS No.	149965-41-3
Molecular Formula	C7H5Br2Cl
Molecular Weight	284.38 g/mol
Synonyms	1-Chloro-4-bromo-2-(bromomethyl)benzene; 2-(Bromomethyl)-4-bromo-1-chlorobenzene; 4-Bromo-2-bromomethyl-1-chlorobenzene; 2,4-Dibromo-α-chlorotoluene; Benzene, 1-chloro-4-bromo-2-(bromomethyl)-; α,2,4-Tribromotoluene (related); 2-Bromomethyl-4-bromochlorobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Bromomethyl)-1-Chlorobenzene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.