Description

Cyclohexanone, 2-(Difluoroacetyl)- (9Ci) CAS NO 149894-28-0 is a specialized fluorinated ketone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic incorporation of fluorine atoms and a reactive ketone moiety, enabling precise molecular modifications for performance enhancement. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors who require building blocks for creating novel active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced potency and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoroacetyl group can impart unique biological activity and environmental persistence profiles.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the development of specialty polymers, coatings, and liquid crystals with tailored thermal, optical, or surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D laboratories for constructing complex molecular architectures, including natural product analogs and fluorinated heterocycles.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution on reactivity and physical properties in ketone chemistry.

Basic Information

Product Name	Cyclohexanone, 2-(Difluoroacetyl)- (9Ci)
CAS No.	149894-28-0
Molecular Formula	C8H10F2O2
Molecular Weight	176.16 g/mol
Synonyms	2-(Difluoroacetyl)cyclohexanone; 1-Cyclohexyl-2,2-difluoroethanone; 2,2-Difluoro-1-cyclohexylethanone; Cyclohexyl difluoroacetyl ketone; Difluoroacetylcyclohexane; 149894-28-0; 2-Difluoroacetylcyclohexanone
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanone, 2-(Difluoroacetyl)- is produced and tested under a strict quality management system to ensure consistency, purity, and traceability. Our standard quality protocol includes comprehensive analytical characterization using techniques such as GC, HPLC, NMR, and FTIR to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support custom purity requirements for specific R&D or scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability, as the compound may be sensitive to decomposition at elevated temperatures. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.