Description

Tetrahydrodemethoxydiferuloylmethane is a specialized curcuminoid derivative, a hydrogenated and demethoxylated analog of diferuloylmethane. This compound is valued for its enhanced stability and modified biological activity profile compared to its parent molecules, making it a critical intermediate and active ingredient in advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and high-performance cosmetic industries for applications in anti-inflammatory formulations, neuroprotective studies, and as a stable antioxidant agent.

Application

• Pharmaceutical Intermediates: Serves as a key building block for synthesizing novel therapeutic agents targeting inflammation and oxidative stress.
• Nutraceutical Research: Investigated for its potential bioactivity in dietary supplements focused on joint health and cognitive support.
• Cosmetic Actives: Used in the formulation of premium skincare products for its potential anti-aging and skin-brightening properties.
• Biochemical Research: Employed as a reference standard and probe in studying cellular signaling pathways related to antioxidant response elements.
• Functional Food Development: Explored as a stabilizing and functional ingredient in health-focused food products.
• Advanced Material Science: Investigated for incorporation into polymeric matrices for controlled-release delivery systems.

Basic Information

Product Name	Tetrahydrodemethoxydiferuloylmethane
CAS No.	149579-07-7
Molecular Formula	C20H20O6
Molecular Weight	356.37 g/mol
Synonyms	1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione; Tetrahydrobisdemethoxycurcumin; Hexahydrocurcumin; Dihydrocurcuminoid I; THDDM; NSC 407303; Curcumin derivative C1; Reduced curcumin analog
EINECS	Contact for details

Quality Control

Our Tetrahydrodemethoxydiferuloylmethane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to pale brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.