Description

3-(4-Bromophenyl)Cyclobutane-1-Carboxylic Acid is a high-purity brominated cyclobutane derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and an aromatic bromine substituent, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bromophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and liquid crystals, where the rigid cyclobutane core imparts specific thermal and optical properties.
• Chemical Biology: Employed in the synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	3-(4-Bromophenyl)Cyclobutane-1-Carboxylic Acid
CAS No.	149506-16-1
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	3-(4-Bromophenyl)cyclobutane-1-carboxylic acid; 4-Bromo-alpha,α-cyclobutanephenylacetic Acid; 1-Cyclobutane-1-carboxylic acid, 3-(4-bromophenyl)-; 3-(p-Bromophenyl)cyclobutanecarboxylic Acid; (3-(4-Bromophenyl)cyclobutyl)formic Acid; 4-Bromophenylcyclobutanecarboxylic Acid; 149506-16-1 (CAS); 3-(4-Bromophenyl)-1-cyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Bromophenyl)Cyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC Area %)	≥98.0% (High Purity Grade)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.