Description

4'-(Aminomethyl)-Biphenyl-2-Carboxylic Acid is a high-purity bifunctional organic intermediate featuring both a carboxylic acid and a primary amine group on a biphenyl scaffold. This unique structure makes it a valuable building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing targeted drug candidates and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological and inflammatory pathways.
• Ligand Synthesis: Used to create sophisticated ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating potential.
• Peptidomimetic Chemistry: Serves as a rigid, aromatic spacer or core structure in the design of peptide mimics and protease inhibitors.
• Polymer Modification: Functional monomer for introducing aromaticity and reactive amine/carboxyl sites into specialty polymers and resins.
• Agrochemical Research: Building block for developing novel herbicides and plant growth regulators with specific activity.
• Diagnostic Reagent Development: Utilized in the conjugation of dyes and probes for immunoassays and biochemical sensing.

Basic Information

Product Name	4'-(Aminomethyl)-Biphenyl-2-Carboxylic Acid
CAS No.	149285-93-8
Molecular Formula	C14H13NO2
Molecular Weight	227.26 g/mol
Synonyms	[2'-(Aminomethyl)[1,1'-biphenyl]-2-carboxylic acid]; 2'-(Aminomethyl)-[1,1'-biphenyl]-2-carboxylic acid; 2-Carboxy-2'-(aminomethyl)biphenyl; Biphenyl-2-carboxylic acid, 4'-(aminomethyl)-; 4-(Aminomethyl)biphenyl-2-carboxylic Acid; (2'-Aminomethyl-biphenyl-2-yl)-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4'-(Aminomethyl)-Biphenyl-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.