Description

1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, Ethyl Ester, (S)- (9Ci) is a high-purity, chiral organosilicon compound of significant interest in advanced synthetic chemistry. Its value lies in its unique structure, which serves as a versatile building block for creating complex molecules with specific stereochemistry. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. The compound, CAS 149181-77-1, is supplied under strict quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Ligand and Catalyst Development: Serves as a precursor for novel organosilicon-based ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty silicon-containing polymers and hybrid organic-inorganic materials.
• Fine Chemical Production: Acts as a building block for the synthesis of complex, high-value specialty chemicals.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic and organometallic chemistry.

Basic Information

Product Name	1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, Ethyl Ester, (S)- (9Ci)
CAS No.	149181-77-1
Molecular Formula	C12H27NO2Si2
Molecular Weight	273.52 g/mol
Synonyms	(S)-Ethyl 2-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propanoate; (S)-Ethyl α-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentan-1-yl)propionate; 1-Aza-2,5-disilacyclopentane-1-acetic acid, α,2,2,5,5-pentamethyl-, ethyl ester, (S)-; Ethyl (S)-2-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propanoate; (S)-1-(1-Ethoxycarbonylethyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane
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Quality Control

Our 1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, Ethyl Ester, (S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.