Description

1-(Trimethylsilyl)-3,4-Dichlorobenzene is a high-purity organosilicon intermediate characterized by its silyl-protected aromatic ring and two chlorine substituents, offering versatile reactivity for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise building blocks for complex molecules in regulated industries. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and advanced materials, where its specific functional groups enable targeted chemical transformations.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic or silyl-protected functional groups.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the reactivity of the dichloro and trimethylsilyl moieties.
• Liquid Crystal & OLED Material Precursor: Acts as a building block for organic electronic materials, where its structure contributes to the desired molecular architecture and electronic properties.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems common in many high-value chemicals.
• Organic Synthesis Reagent: Provides a protected phenol equivalent or a directing group in multi-step synthetic routes for fine chemicals and specialty polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel compound libraries.

Basic Information

Product Name	1-(Trimethylsilyl)-3,4-Dichlorobenzene
CAS No.	149021-03-4
Molecular Formula	C9H12Cl2Si
Molecular Weight	219.18 g/mol
Synonyms	3,4-Dichloro-1-(trimethylsilyl)benzene; 3,4-Dichlorophenyltrimethylsilane; Trimethyl(3,4-dichlorophenyl)silane; Benzene, 1-(trimethylsilyl)-3,4-dichloro-; (3,4-Dichlorophenyl)trimethylsilane; TMS-3,4-Dichlorobenzene; 3,4-Dichloro-1-trimethylsilylbenzene
EINECS	Contact for details

Quality Control

Our production of 1-(Trimethylsilyl)-3,4-Dichlorobenzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting full specifications are available for all commercial quantities, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.