Description

Bicyclo[1.1.1]pentane-1,3-diamine is a highly strained, rigid bicyclic diamine building block of significant interest in modern organic and medicinal chemistry. Its unique three-dimensional scaffold is prized for its ability to impart favorable physicochemical properties, such as improved metabolic stability and solubility, into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel bioactive compounds and advanced materials.

Application

• Pharmaceutical Intermediates: A key building block for synthesizing drug candidates with enhanced 3D character, potentially improving target engagement and ADMET profiles.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its rigid structure can contribute to biological activity and environmental stability.
• Ligand and Catalyst Design: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Incorporated as a monomer or cross-linker to produce polymers with unique thermal and mechanical properties.
• Peptidomimetics: Acts as a constrained diamine surrogate in peptide analogs to stabilize specific conformations and resist enzymatic degradation.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tools for studying biological systems and protein-ligand interactions.

Basic Information

Product Name	Bicyclo[1.1.1]pentane-1,3-diamine
CAS No.	148561-75-5
Molecular Formula	C5H10N2
Molecular Weight	98.15 g/mol
Synonyms	1,3-Diaminobicyclo[1.1.1]pentane; BCP-diamine; [1.1.1]Propellane-1,3-diamine; 3-Aminobicyclo[1.1.1]pentan-1-amine; Bicyclo[1.1.1]pentane-1,3-diyldiamine; BCP-NH2; 1,3-BCP-diamine
EINECS	Contact for details

Quality Control

Our Bicyclo[1.1.1]pentane-1,3-diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.