Description

2H-Pyran-2-Aceticacid,6-Ethoxytetrahydro-3-Hydroxy-,[2R-(2Alpha,3Bta,6Bta)]-(9Ci) CAS NO 148379-84-4 is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its complex pyran-acetic acid structure makes it a valuable building block for constructing sophisticated molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex, stereospecific drug molecules.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active compounds for crop protection and pest management solutions.
• Academic & Industrial Research: Serves as a critical reagent in methodological studies and synthetic route exploration for complex heterocyclic systems.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where high stereochemical purity and specific functional groups are required.
• Process Chemistry Development: Utilized for scaling up synthetic pathways from laboratory to pilot plant and commercial production.

Basic Information

Product Name	2H-Pyran-2-Aceticacid,6-Ethoxytetrahydro-3-Hydroxy-,[2R-(2Alpha,3Bta,6Bta)]-(9Ci)
CAS No.	148379-84-4
Molecular Formula	C9H16O5
Molecular Weight	204.22 g/mol
Synonyms	(2R,3R,6R)-6-Ethoxy-3-hydroxytetrahydro-2H-pyran-2-acetic acid; 6-Ethoxytetrahydro-3-hydroxy-2H-pyran-2-acetic acid, (2R,3R,6R)-; (2R,3R,6R)-6-Ethoxy-3-hydroxytetrahydro-2H-pyran-2-ylacetic acid; Tetrahydro-6-ethoxy-3-hydroxy-2H-pyran-2-acetic acid, (2R,3R,6R)-; 148379-84-4; (2R,3R,6R)-6-Ethoxy-3-hydroxytetrahydropyran-2-acetic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high stereochemical purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral chromatography, NMR, and mass spectrometry to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.