Description

1,2-Cyclopropanedicarboxylicacid,1-(1-Methylethyl)-,(1R-Cis)-(9Ci) is a high-purity, chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of complex, biologically active molecules, offering a rigid, three-dimensional scaffold. It is primarily utilized by pharmaceutical research and agrochemical industries for the synthesis of novel active ingredients, where its specific stereochemistry is essential for target interaction.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane ring enhances stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique structural properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid,1-(1-Methylethyl)-,(1R-Cis)-(9Ci)
CAS No.	148261-92-1
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1R,2S)-1-Isopropylcyclopropane-1,2-dicarboxylic Acid; (1R-cis)-1-(1-Methylethyl)-1,2-Cyclopropanedicarboxylic Acid; cis-1-Isopropylcyclopropane-1,2-dicarboxylic Acid; 1-Isopropyl-1,2-cyclopropanedicarboxylic acid, (1R,2S)-rel-; Chiral Cyclopropane Dicarboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including Chiral HPLC, NMR, and specific rotation measurements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.