Description

(E)-4-Bromo-1-Morpholinobut-2-En-1-One is a high-purity, versatile chemical intermediate featuring a brominated α,β-unsaturated ketone moiety linked to a morpholine ring. This compound is valued for its unique reactivity profile, serving as a key building block in complex organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition or other therapeutic pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: The reactive bromo and enone groups make it suitable for cross-coupling reactions (e.g., Suzuki, Heck) and Michael additions.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	(E)-4-Bromo-1-Morpholinobut-2-En-1-One
CAS No.	148147-64-2
Molecular Formula	C8H12BrNO2
Molecular Weight	234.09 g/mol
Synonyms	4-Bromo-1-morpholinobut-2-en-1-one; (E)-4-Bromo-1-morpholinobut-2-en-1-one; 4-Bromo-1-(morpholin-4-yl)but-2-en-1-one; 4-Bromobut-2-enoyl morpholine; 4-Bromo-1-morpholino-2-buten-1-one; 148147-64-2; 4-Bromo-N-morpholinocrotonamide (related tautomer)
EINECS	Contact for details

Quality Control

Our (E)-4-Bromo-1-Morpholinobut-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.