Description

Polyvinylbenzyl Glucaro(1,4)Lactonate is a specialized functional polymer derivative, synthesized by grafting glucaro-1,4-lactone onto a polyvinylbenzyl backbone. This compound matters for its unique combination of polymeric stability and the specific chelating and cross-linking properties imparted by the glucarolactone moiety. It is primarily needed by manufacturers in the pharmaceutical, advanced material science, and specialty chemical industries for applications requiring controlled release, metal ion binding, or as a reactive intermediate for further polymer functionalization.

Application

• Pharmaceutical Excipient: Used as a functional polymer carrier in controlled drug delivery systems and for taste masking.
• Chelating Resin Precursor: Serves as a key intermediate in the synthesis of resins designed for selective metal ion recovery or purification in hydrometallurgy and wastewater treatment.
• Cross-linking Agent: Employed in the formulation of specialty coatings, adhesives, and hydrogels where biodegradable or pH-sensitive cross-links are desired.
• Analytical Chemistry: Utilized as a stationary phase modifier in chromatography for the separation of chiral compounds or specific metal complexes.
• Biomaterial Fabrication: Incorporated into scaffolds and matrices for tissue engineering due to its potential biocompatibility and modifiable surface properties.
• Polymer Modification: Acts as a reactive handle to introduce carbohydrate-derived functionalities onto polymer surfaces, altering hydrophilicity and bio-interaction profiles.

Basic Information

Product Name	Polyvinylbenzyl Glucaro(1,4)Lactonate
CAS No.	148005-77-0
Molecular Formula	(C15H16O6)n (Representative monomer unit)
Molecular Weight	Variable (Polymer)
Synonyms	Poly(vinylbenzyl glucarolactonate); PVB-GL; Glucaro-1,4-lactone, polymer with chloromethylstyrene; Poly(styrene-co-vinylbenzyl glucaro-1,4-lactonate); 4-O-(4-Vinylbenzyl) D-glucaro-1,4-lactone polymer; Glucarolactone-functionalized polystyrene; Poly(vinylbenzyl D-glucaro-1,4:6,3-dilactone) (related structure)
EINECS	Contact for details

Quality Control

Our Polyvinylbenzyl Glucaro(1,4)Lactonate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure consistency in degree of functionalization, molecular weight distribution, and purity. Certificates of Analysis (COA) are provided, detailing key parameters such as assay, residual monomer content, and identity confirmation. We support compliance with cGMP and ISO 9001 standards for relevant applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent moisture uptake and potential hydrolysis of the lactone moiety. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (Functional Group)	≥ 85% (by titration/NMR)
Degree of Substitution	Contact for details
Weight Average Molecular Weight (Mw)	5,000 - 50,000 Da (Customizable)
Polydispersity Index (PDI)	< 2.5
Loss on Drying	≤ 2.0 %
Residual Monomer (HPLC)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.