Description

1-(2-Naphthylsulfonyl)-4-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonamide-piperidine-carboxylic acid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those with sulfonamide-based pharmacophores.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its structural similarity to transition-state analogs.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study protein-protein interactions and enzyme function.
• Organic Synthesis: Employed in academic and industrial research for constructing complex heterocyclic compounds and peptidomimetics.
• Material Science Research: Potential precursor for specialty polymers or ligands in catalyst systems.

Basic Information

Product Name	1-(2-Naphthylsulfonyl)-4-Piperidinecarboxylic Acid
CAS No.	147959-02-2
Molecular Formula	C16H15NO4S
Molecular Weight	317.36 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(2-naphthalenesulfonyl)-; 1-(Naphthalene-2-sulfonyl)piperidine-4-carboxylic acid; 1-(2-Naphthylsulfonyl)isonipecotic acid; 1-(2-Naphthalenesulfonyl)piperidine-4-carboxylic acid; NSC 339586; 1-(Naphthalen-2-ylsulfonyl)piperidine-4-carboxylic acid; 1-(2-Naphthylsulfonyl)-4-carboxypiperidine
EINECS	Contact for details

Quality Control

Our 1-(2-Naphthylsulfonyl)-4-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.