Description

1,1Bis[(2R,5R)-2,5-Diethylphospholano]Ferrocene, Min. 97% is a high-purity, chiral ferrocenyl phosphine ligand. This compound matters as a critical catalyst component for asymmetric synthesis, enabling the production of enantiomerically pure intermediates in pharmaceuticals and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high selectivity and yield in hydrogenation and cross-coupling reactions.

Application

• Asymmetric Hydrogenation Catalysis: A key ligand for rhodium or ruthenium complexes used in the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profile.
• Cross-Coupling Reactions: Facilitates asymmetric C-C and C-X bond-forming reactions, such as Suzuki-Miyaura and Heck reactions, for complex molecule construction.
• Fine Chemical and Flavor/Fragrance Production: Applied in the synthesis of high-value chiral compounds for specialty chemicals, flavors, and aromas.
• Academic and Industrial R&D: Serves as a versatile tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	1,1Bis[(2R,5R)-2,5-Diethylphospholano]Ferrocene, Min. 97%
CAS No.	147762-89-8
Molecular Formula	C24H38FeP2
Molecular Weight	444.35 g/mol
Synonyms	(R,R)-1,1'-Bis(2,5-diethylphospholano)ferrocene; Josiphos SL-J009-1; (R,R)-2,2'-Bis(2,5-diethylphospholano)-1,1'-biferrocene; (R,R)-DIPPF; (2R,5R)-1,1'-Bis(2,5-diethylphospholanyl)ferrocene; (R,R)-1,1'-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene; Chiral Ferrocenyl Diphosphine Ligand
EINECS	Contact for details

Quality Control

Our 1,1Bis[(2R,5R)-2,5-Diethylphospholano]Ferrocene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure a minimum purity of 97% and confirm stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures must be avoided to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0%
Loss on Drying	Max. 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.