Description

1,2-Dieicosanoyl-Sn-Glycerol is a synthetic, high-purity glycerolipid where the sn-1 and sn-2 positions of the glycerol backbone are esterified with eicosanoic (arachidic) acid. This specific molecular architecture makes it a valuable reference standard and a critical building block for advanced lipid research and formulation. It is essential for scientists and manufacturers requiring precise, well-defined lipid structures. Key applications include its use as a standard in analytical chemistry, a precursor in lipidomics, and a component in the development of specialized lipid-based delivery systems and biomimetic membranes.

Application

• Analytical Reference Standard: Used for the identification, calibration, and quantification of complex lipids in mass spectrometry (MS), high-performance liquid chromatography (HPLC), and other analytical techniques in lipidomics.
• Biochemical Research: Serves as a critical substrate or model compound for studying enzyme kinetics (e.g., lipases, phospholipases), membrane biophysics, and lipid metabolism pathways.
• Pharmaceutical Development: Acts as a key intermediate or structural component in the synthesis of novel prodrugs, lipid nanoparticles (LNPs), and other advanced drug delivery vehicles.
• Biomimetic Membrane Systems: Incorporated into liposomes and other artificial membrane constructs to study membrane fluidity, protein-lipid interactions, and cellular processes.
• Specialty Chemical Synthesis: Utilized as a building block for the synthesis of more complex, structured lipids, surfactants, and functional polymers with tailored properties.
• Cosmetic & Dermatological Formulations: Employed in high-end skincare products as an emollient and skin-identical lipid to support barrier function and delivery of active ingredients.

Basic Information

Product Name	1,2-Dieicosanoyl-Sn-Glycerol
CAS No.	147514-21-4
Molecular Formula	C43H84O5
Molecular Weight	681.13 g/mol
Synonyms	1,2-Diarachidoyl-sn-glycerol; sn-Glycerol 1,2-diarachidate; 1,2-Dieicosanoin; 1,2-Di-O-eicosanoyl-sn-glycerol; 1,2-Di-C20:0-sn-glycerol; Arachidic acid 1,2-diglyceride; DG(20:0/20:0); 1,2-Di-O-icosanoyl-sn-glycerol
EINECS	Contact for details

Quality Control

Our 1,2-Dieicosanoyl-Sn-Glycerol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles are provided with every shipment. We support compliance with relevant regulatory frameworks for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. For long-term storage, desiccate to prevent moisture absorption. Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.