Description

1-(3,4-Dimethoxyphenyl)Cyclobutanecarboxylic Acid is a high-purity synthetic intermediate featuring a cyclobutane ring fused with a dimethoxyphenyl moiety. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for constructing complex molecules with specific stereochemistry and functional group arrays. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing complex polycyclic architectures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the dimethoxyphenyl group is a critical pharmacophore.
• Material Science Chemistry: Serves as a monomer or functionalized unit in the research of advanced polymers, liquid crystals, or organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic chemistry, such as ring-strain utilization or cross-coupling reactions.
• Fine Chemical Synthesis: Acts as a starting material for the production of specialty chemicals, flavors, and fragrances requiring specific aromatic substitution patterns.

Basic Information

Product Name	1-(3,4-Dimethoxyphenyl)Cyclobutanecarboxylic Acid
CAS No.	147406-22-2
Molecular Formula	C₁₃H₁₆O₄
Molecular Weight	236.26 g/mol
Synonyms	Cyclobutanecarboxylic acid, 1-(3,4-dimethoxyphenyl)-; 1-(3,4-Dimethoxyphenyl)cyclobutane-1-carboxylic acid; 3,4-Dimethoxybenzenecarboxylic acid cyclobutyl ester (related); Veratrole Cyclobutanecarboxylate Derivative; (3,4-Dimethoxyphenyl)cyclobutanecarboxylic Acid; NSC 405124; Aromatic Cyclobutane Carboxylic Acid Ester Intermediate
EINECS	Contact for details

Quality Control

Our production of 1-(3,4-Dimethoxyphenyl)Cyclobutanecarboxylic Acid adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.