Description

6-Selenomethylcholesterol is a synthetic, organoselenium-modified sterol compound, distinguished by the substitution of a selenium-containing methyl group at the 6-position of the cholesterol backbone. This structural modification makes it a valuable biochemical tool and a key intermediate in the research of selenium's role in biological systems, particularly in antioxidant mechanisms and lipid metabolism. It is primarily utilized by research institutions and pharmaceutical development teams focused on metabolic studies, novel therapeutic agent synthesis, and advanced biochemical assay development.

Application

• Biochemical Research: Used as a standard or probe in studies investigating the biological activity and metabolism of selenium-containing sterols and lipids.
• Pharmaceutical Intermediates: Serves as a key synthetic building block for the development of novel therapeutic agents targeting oxidative stress or metabolic disorders.
• Metabolic Pathway Analysis: Employed in tracer studies to elucidate the incorporation and role of selenium in cholesterol-related metabolic pathways.
• Antioxidant Mechanism Studies: Acts as a model compound to study the antioxidant properties of organoselenium compounds in lipid membranes and cellular systems.
• Reference Standard: Used as a high-purity analytical reference standard in HPLC, LC-MS, or NMR for quality control and method validation in research settings.

Basic Information

Product Name	6-Selenomethylcholesterol
CAS No.	146883-72-9
Molecular Formula	C28H48OSe
Molecular Weight	487.63 g/mol
Synonyms	6-(Methylseleno)cholesterol; Cholest-5-en-3β-ol, 6-(methylseleno)-; 6-Methylselenocholesterol; 6-Se-Methylcholesterol; 6-Selenomethylenecholesterol; 6-(Selenomethyl)cholesterol
EINECS	Contact for details

Quality Control

Our 6-Selenomethylcholesterol is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.