Description

4(1H)-Pyridazinone, 6-Methyl-3-(2-Quinolinylmethoxy)-1-(3-(Trifluoromethyl)Phenyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique pyridazinone-quinoline hybrid scaffold.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific enzyme interactions or receptor binding.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and the development of new heterocyclic methodologies.

Basic Information

Product Name	4(1H)-Pyridazinone, 6-Methyl-3-(2-Quinolinylmethoxy)-1-(3-(Trifluoromethyl)Phenyl)-
CAS No.	146824-84-2
Molecular Formula	C22H16F3N3O2
Molecular Weight	411.38 g/mol
Synonyms	6-Methyl-3-(2-quinolinylmethoxy)-1-[3-(trifluoromethyl)phenyl]-4(1H)-pyridazinone; 1-(3-(Trifluoromethyl)phenyl)-6-methyl-3-(quinolin-2-ylmethoxy)pyridazin-4(1H)-one; 6-Methyl-3-(quinolin-2-ylmethoxy)-1-(3-(trifluoromethyl)phenyl)pyridazin-4(1H)-one; CAS 146824-84-2; 4(1H)-Pyridazinone derivative with quinoline; Trifluoromethylphenyl pyridazinone quinoline ether
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with identity confirmed by spectroscopic methods. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment. We can support development projects with custom purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.