Description

Ethyl trans-5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant chiral building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in the construction of complex molecular scaffolds for biological screening and lead optimization.
• Process Chemistry: Serves as a building block in the scale-up and route development for candidate drugs.
• Organic Synthesis: Employed in academic and industrial research for the synthesis of heterocyclic compounds and natural product analogs.
• Chemical Biology: Can be utilized in the synthesis of probes and tool compounds for studying biological pathways.

Basic Information

Product Name	Ethyl trans-5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride
CAS No.	146689-73-8
Molecular Formula	C9H18ClNO3
Molecular Weight	223.70 g/mol
Synonyms	Ethyl (2R,5S)-5-Aminotetrahydro-2H-pyran-2-carboxylate hydrochloride; Ethyl trans-5-Aminotetrahydropyran-2-carboxylate HCl; 5-Amino-tetrahydropyran-2-carboxylic acid ethyl ester hydrochloride; 2H-Pyran-2-carboxylic acid, 5-amino-tetrahydro-, ethyl ester, hydrochloride, (2R,5S)-rel-; (2R,5S)-5-Aminotetrahydro-2H-pyran-2-carboxylic Acid Ethyl Ester Hydrochloride; trans-5-Amino-tetrahydropyran-2-carboxylic acid ethyl ester hydrochloride; 146689-73-8
EINECS	Contact for details

Quality Control

Our Ethyl trans-5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.