Description

(S)-4-Ethyl-4-Hydroxy-1H-Pyrano[3,4-C]Pyridine-3,8(4H,7H)-Dione is a high-purity, chiral pyranopyridinedione derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with defined chirality.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides.
• Ligand and Catalyst Development: Used in the design of novel chiral ligands and organocatalysts for catalytic processes.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and discovery chemistry.
• Fine Chemical Production: Incorporated into the synthesis of specialty chemicals, dyes, and advanced materials.

Basic Information

Product Name	(S)-4-Ethyl-4-Hydroxy-1H-Pyrano[3,4-C]Pyridine-3,8(4H,7H)-Dione
CAS No.	146683-25-2
Molecular Formula	C₁₁H₁₃NO₄
Molecular Weight	223.23 g/mol
Synonyms	(4S)-4-Ethyl-4-hydroxy-1H,4H,7H,8H-pyrano[3,4-c]pyridine-3,8-dione; (S)-4-Ethyl-4-hydroxy-4,7-dihydro-1H-pyrano[3,4-c]pyridine-3,8-dione; 4-Ethyl-4-hydroxy-1H-pyrano[3,4-c]pyridine-3,8(4H,7H)-dione, (S)-; L-694,247 intermediate; Pyranopyridinedione derivative; Chiral pyranone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (S)-4-Ethyl-4-Hydroxy-1H-Pyrano[3,4-C]Pyridine-3,8(4H,7H)-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity (enantiomeric excess), and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.