Description

(-)-(1R,2R,5S)-Neomenthyl Acetate is a high-purity, chiral ester derivative of menthol, valued for its distinct olfactory profile and stereochemical purity. This compound is a critical intermediate and aroma chemical, prized for its stability and consistent performance in advanced formulations. It is essential for manufacturers in the fragrance, flavor, and pharmaceutical industries seeking reliable, high-quality chiral building blocks.

Application

• Fragrance & Perfumery: Used as a key chiral ingredient in fine fragrances, imparting fresh, minty, and woody notes with excellent fixative properties.
• Flavoring Agent: Employed in the synthesis of sophisticated flavor compounds for food, beverages, and oral care products.
• Pharmaceutical Intermediate: Serves as a valuable chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Chemical Synthesis: Acts as a versatile starting material or auxiliary in organic synthesis, particularly in reactions requiring stereochemical control.
• Research & Development: Utilized in academic and industrial R&D for studying chiral recognition, catalysis, and developing new synthetic methodologies.

Basic Information

Product Name	(-)-(1R,2R,5S)-Neomenthyl Acetate
CAS No.	146502-80-9
Molecular Formula	C₁₂H₂₂O₂
Molecular Weight	198.30 g/mol
Synonyms	(-)-Neomenthyl Acetate; (1R,2R,5S)-2-Isopropyl-5-methylcyclohexyl Acetate; L-Neomenthyl Acetate; (1R,2R,5S)-Neomenthol Acetate; Neomenthyl Acetate; trans-2-Isopropyl-5-methylcyclohexyl Acetate; (1R,2R,5S)-1-Methyl-4-(1-methylethyl)cyclohexan-2-yl Acetate
EINECS	Contact for details

Quality Control

Our (-)-(1R,2R,5S)-Neomenthyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets exacting specifications for the fragrance, flavor, and pharmaceutical sectors. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Chiral Purity (GC/HPLC)	≥ 99.0% ee
Specific Rotation [α]D20	-70° to -80° (c=1 in CHCl₃)
Refractive Index nD20	1.445 - 1.455
Density (g/mL, 20°C)	0.910 - 0.930

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.