Description

4-(Aminomethyl)Chroman-4-Ol is a chiral amino alcohol derivative of chroman, serving as a versatile and valuable building block in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its chiral center for enhanced biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and flavor compounds, and other high-value specialty chemicals.
• Academic and R&D: A valuable reagent for medicinal chemistry research and process development in university and industrial laboratories.

Basic Information

Product Name	4-(Aminomethyl)Chroman-4-Ol
CAS No.	146471-52-5
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	4-(Aminomethyl)-4-hydroxy-2,3-dihydro-1-benzopyran; 4-Hydroxy-4-(aminomethyl)chroman; 4-(Aminomethyl)-4-hydroxychroman; 4-(Aminomethyl)chroman-4-ol; 4-Hydroxychroman-4-methylamine; 4-(Aminomethyl)-3,4-dihydro-2H-1-benzopyran-4-ol
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Chroman-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.