Description

Sakacin P is a Class IIa bacteriocin, a natural antimicrobial peptide primarily produced by certain strains of *Lactobacillus*. This compound is valued for its potent and targeted activity against Gram-positive foodborne pathogens, particularly *Listeria monocytogenes*. It serves as a critical tool for manufacturers in the food and beverage industry seeking natural, label-friendly preservation solutions to enhance product safety and shelf life. Its application is also explored in pharmaceutical and biomedical research for its antimicrobial properties.

Application

• Food Preservation: Used as a natural biopreservative in dairy products (cheese, yogurt), meats (cured and fermented sausages), and ready-to-eat foods to inhibit *Listeria* and other spoilage bacteria.
• Starter Culture Component: Incorporated into protective fermentative cultures to improve the safety and consistency of fermented food production.
• Active Packaging: Integrated into edible films and food packaging materials to create antimicrobial surfaces that extend shelf life.
• Biomedical Research: Studied for its mode of action, potential synergies with other antimicrobials, and applications in controlling bacterial infections.
• Veterinary and Feed Applications: Explored as an alternative to antibiotics in animal feed for gut health management and pathogen control.

Basic Information

Product Name	Sakacin P
CAS No.	146240-19-9
Molecular Formula	C152H246N44O43S2 (Representative for major variant)
Molecular Weight	~3486.0 g/mol (for major variant)
Synonyms	Sakacin P; Bacteriocin P; Lactocin P; Anti-listerial bacteriocin P; Class IIa bacteriocin; Pediocin-like bacteriocin; *Lactobacillus saké* bacteriocin P
EINECS	Contact for details

Quality Control

Our Sakacin P is produced and handled under stringent quality management systems. Each batch is subjected to rigorous analytical testing to ensure identity, purity, and consistent biological activity. Certificates of Analysis (COA) detailing purity, potency (activity units), and microbiological safety are provided. We adhere to relevant quality standards suitable for research and food-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed container to reach room temperature before opening to prevent condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Potency (Activity Assay)	≥ 10,000 AU/mg (vs. *Listeria innocua*)
Moisture Content (KF)	≤ 5.0 %
Endotoxin (LAL)	< 10 EU/mg
Microbial Limits	Absence of specified pathogens

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.