Description

(2R,3S,4R)-4-(Benzyloxy)-2-((Benzyloxy)Methyl)-3-Methoxy-3,4-Dihydro-2H-Pyran is a high-purity, chiral carbohydrate derivative and a key protected intermediate in organic synthesis. Its precise stereochemistry makes it a critical building block for the development of complex, biologically active molecules, ensuring high enantiomeric purity in final products. This compound is essential for research and production in pharmaceutical development, particularly for antiviral and anticancer agents, as well as in advanced fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of novel antiviral compounds targeting specific viral enzymes.
• Glycochemistry & Glycobiology: Serves as a protected glycosyl donor or acceptor for constructing complex carbohydrate structures and glycoconjugates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block to induce stereoselectivity in complex organic transformations.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies and lead optimization for new therapeutic candidates.
• Fine Chemical Production: Acts as a specialized intermediate for custom synthesis and contract manufacturing of high-value chemicals.

Basic Information

Product Name	(2R,3S,4R)-4-(Benzyloxy)-2-((Benzyloxy)Methyl)-3-Methoxy-3,4-Dihydro-2H-Pyran
CAS No.	145852-77-3
Molecular Formula	C21H24O5
Molecular Weight	356.41 g/mol
Synonyms	4-O-Benzyl-2-O-benzyloxymethyl-3-O-methyl-3,4-dihydro-2H-pyran; (2R,3S,4R)-4-(Benzyloxy)-2-((benzyloxy)methyl)-3-methoxy-3,4-dihydro-2H-pyran; 3,4-Dihydro-2H-pyran, 4-(benzyloxy)-2-((benzyloxy)methyl)-3-methoxy-, (2R,3S,4R)-; Benzyl 2-O-benzyloxymethyl-3-O-methyl-α-D-erythro-pent-2-enopyranoside; Protected Dihydroxypyran Intermediate; Chiral Dihydropyran Derivative
EINECS	Contact for details

Quality Control

Our (2R,3S,4R)-4-(Benzyloxy)-2-((Benzyloxy)Methyl)-3-Methoxy-3,4-Dihydro-2H-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.