Description

Ethyl (1S,5R)-2-Oxo-3-Oxabicyclo[3.1.0]Hexane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic lactone structure. This compound is of significant value for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, particularly in antiviral and central nervous system (CNS) therapeutic research.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing bicyclic frameworks and introducing specific stereochemistry.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes under GMP conditions.
• Academic & Contract Research: Employed in research laboratories for method development, exploring new synthetic pathways, and creating proprietary compound libraries.
• Agrochemical Research: Potential application as an intermediate in the development of novel, high-value crop protection agents with specific biological activity.

Basic Information

Product Name	Ethyl (1S,5R)-2-Oxo-3-Oxabicyclo[3.1.0]Hexane-1-Carboxylate
CAS No.	145032-58-2
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	(1S,5R)-Ethyl 2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate; (-)-Ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate; Ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hex-1-ylcarboxylate; 3-Oxabicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, ethyl ester, (1S,5R)-; Bicyclic Lactone Ester Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl (1S,5R)-2-Oxo-3-Oxabicyclo[3.1.0]Hexane-1-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) confirming identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.