Description

[5-(Toluene-4-Sulfonyloxy)-Pentyloxy]-Acetic Acid tert-Butyl Ester is a specialized organic intermediate featuring a tosylate-protected alcohol and a tert-butyl ester group, making it a valuable building block for complex organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for applications such as linker chemistry, prodrug synthesis, and the construction of functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for creating prodrugs or incorporating specific functional groups.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring tailored molecular structures.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers with specific chemical or physical properties.
• Linker Chemistry: The tosylate group acts as a versatile leaving group for nucleophilic substitution reactions, enabling the attachment of various molecular fragments.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for constructing complex ether and ester derivatives.
• Peptide Mimetics: Potential use in the design and synthesis of peptide analogs and other bio-active compounds.

Basic Information

Product Name	[5-(Toluene-4-Sulfonyloxy)-Pentyloxy]-Acetic Acid tert-Butyl Ester
CAS No.	144682-06-4
Molecular Formula	C18H28O6S
Molecular Weight	372.48 g/mol
Synonyms	tert-Butyl [5-[(4-methylphenyl)sulfonyl]oxy]pentoxy]acetate; 2-(5-((4-Methylphenyl)sulfonyloxy)pentoxy)acetic acid tert-butyl ester; 5-[(p-Toluenesulfonyl)oxy]pentyloxyacetic acid tert-butyl ester; Acetic acid, 2-[5-[(4-methylphenyl)sulfonyl]oxy]pentoxy]-, 1,1-dimethylethyl ester; Tosyloxy-PEG5-t-butyl ester (analogous naming convention)
EINECS	Contact for details

Quality Control

Our [5-(Toluene-4-Sulfonyloxy)-Pentyloxy]-Acetic Acid tert-Butyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.