Description

5-(4'-Amidinophenoxy)Pentanoic Acid is a high-purity synthetic organic compound featuring a distinctive amidinophenoxy linker attached to a pentanoic acid chain. This structure makes it a valuable intermediate and building block in advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors, particularly targeting enzymes like thrombin and trypsin.
• Bioconjugation & Linker Chemistry: Serves as a versatile heterobifunctional linker for coupling biomolecules (e.g., peptides, antibodies) to other entities, leveraging its carboxylic acid and amidine groups.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with improved potency and selectivity.
• Diagnostic Reagent Development: Employed in the design and production of affinity ligands and probes for diagnostic assays.
• Chemical Biology Tool: Acts as a precursor for activity-based probes to study enzyme function and mechanism in biological systems.
• Fine Chemical Synthesis: Intermediate for creating more complex molecules with specific biological activities in custom synthesis projects.

Basic Information

Product Name	5-(4'-Amidinophenoxy)Pentanoic Acid
CAS No.	144602-61-9
Molecular Formula	C₁₂H₁₆N₂O₃
Molecular Weight	236.27 g/mol
Synonyms	4'-Amidinophenoxypentanoic Acid; 5-(4-Amidinophenoxy)valeric Acid; 4-Carbamimidoylphenoxy Pentanoic Acid; 5-[4-(Carbamimidoyl)phenoxy]pentanoic Acid; (4-Carbamimidoylphenoxy)pentanoic Acid; 144602-61-9; 5-(4-Amidinophenoxy)pentanoic acid
EINECS	Contact for details

Quality Control

Our 5-(4'-Amidinophenoxy)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.