Description

7,7-Dimethyl-2-thioxo-1,5,7,8-tetrahydro-2H-pyrano[4,3-b]pyridine-3-carbonitrile is a high-purity, specialized heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its unique fused pyranopyridine structure with a nitrile and thioxo group makes it a valuable intermediate for pharmaceutical research and fine chemical manufacturing. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules. We supply this compound with stringent quality control to ensure batch-to-batch consistency for your most demanding applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe: Acts as a scaffold for creating tool compounds to study enzyme function and biological pathways.
• Material Science: Potential building block for advanced organic materials, such as ligands for catalysis or components in organic electronics.
• Academic & Industrial R&D: Employed in method development and discovery chemistry within university laboratories and corporate research centers.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke chemicals for clients.

Basic Information

Product Name	7,7-Dimethyl-2-thioxo-1,5,7,8-tetrahydro-2H-pyrano[4,3-b]pyridine-3-carbonitrile
CAS No.	144291-93-0
Molecular Formula	C12H12N2OS
Molecular Weight	232.30 g/mol
Synonyms	7,7-Dimethyl-2-thioxo-2,5,7,8-tetrahydro-1H-pyrano[4,3-b]pyridine-3-carbonitrile; 2H-Pyrano[4,3-b]pyridine-3-carbonitrile, 1,5,7,8-tetrahydro-7,7-dimethyl-2-thioxo-; 144291-93-0; Pyrano[4,3-b]pyridine-3-carbonitrile derivative; 3-Cyano-7,7-dimethyl-2-thioxo-1,2,5,7,8,8a-hexahydropyrano[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 7,7-Dimethyl-2-thioxo-1,5,7,8-tetrahydro-2H-pyrano[4,3-b]pyridine-3-carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and conformity to specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request. We are committed to supplying material that meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.