Description

5-Hydroxy-6-Phenylpyridazin-3(2H)-One is a high-purity pharmaceutical intermediate and heterocyclic building block of significant interest in modern organic synthesis. Its core value lies in its versatile pyridazinone scaffold, which is a privileged structure for developing bioactive molecules with targeted therapeutic effects. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a key building block for developing new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing complex polycyclic frameworks and functionalized heterocycles.
• Material Science Research: Investigated for potential use in creating organic electronic materials or metal-organic frameworks (MOFs) due to its coordinating hydroxyl group and aromatic system.
• Academic & R&D Laboratories: Employed in fundamental research to study reaction mechanisms, heterocyclic chemistry, and structure-activity relationships (SAR).

Basic Information

Product Name	5-Hydroxy-6-Phenylpyridazin-3(2H)-One
CAS No.	144284-87-7
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	6-Phenyl-5-hydroxypyridazin-3(2H)-one; 5-Hydroxy-6-phenyl-3(2H)-pyridazinone; 5-Hydroxy-6-phenyl-2,3-dihydropyridazin-3-one; 5-Hydroxy-6-phenylpyridazin-3-one; 3(2H)-Pyridazinone, 5-hydroxy-6-phenyl-; 144284-87-7 (CAS); 5-Hydroxy-6-phenyl-1,2-dihydropyridazine-3-one
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-6-Phenylpyridazin-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.