Description

N,N,n-Trimethyl-N'-Cholesteryl Amidoethyl Ammonium is a specialized quaternary ammonium compound featuring a cholesteryl moiety, offering unique amphiphilic properties. This structure makes it highly valuable for applications requiring precise surface modification and molecular self-assembly. It is particularly sought after by researchers and formulators in the pharmaceutical and advanced materials sectors for developing targeted delivery systems and functional nanomaterials.

Application

• Pharmaceutical Research: As a key component in the synthesis of novel cationic liposomes and lipid nanoparticles (LNPs) for nucleic acid (e.g., mRNA, siRNA) and drug delivery.
• Gene Therapy Vectors: Utilized to create non-viral transfection agents that facilitate cellular uptake of genetic material.
• Biomimetic Materials: Serves as a building block for constructing synthetic membranes and vesicles that mimic biological structures.
• Surface Chemistry: Acts as a functional surfactant or modifier to alter surface energy and promote specific interactions on material interfaces.
• Cosmetic Formulations: Potential use in advanced skincare products as a conditioning agent or encapsulation material for active ingredients.
• Diagnostic Agents: Can be incorporated into contrast agents or probes for medical imaging applications.

Basic Information

Item	Details
Product Name	N,N,n-Trimethyl-N'-Cholesteryl Amidoethyl Ammonium
CAS No.	144108-31-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cholesteryl-TMA Cationic Lipid; 3β-[N-(N',N',N'-Trimethylaminoethyl)carbamoyl]cholest-5-ene; N-Cholesteryloxycarbonyl-N,N,N-trimethylethylenediammonium; Trimethyl-[2-[(3β)-cholest-5-en-3-yloxycarbonylamino]ethyl]ammonium; Cationic Cholesterol Derivative; TM-Chol; Chol-TMA; Lipophilic Quaternary Ammonium Salt
EINECS	Contact for details

Quality Control

Our N,N,n-Trimethyl-N'-Cholesteryl Amidoethyl Ammonium is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.