Description

2-Amino-7,7-Dimethyl-4-(3-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value, multifunctional heterocyclic building block with a complex chromene core structure. This compound is significant for its role as a key synthetic intermediate in the development of novel pharmaceuticals and advanced organic materials. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its complex heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex chromene and fused-ring systems due to its reactive amino and nitrile functional groups.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors, nonlinear optical (NLO) materials, and fluorescent dyes.
• Catalyst and Ligand Development: Potential use in designing novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Amino-7,7-Dimethyl-4-(3-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	144036-36-2
Molecular Formula	C18H17N3O3
Molecular Weight	323.35 g/mol
Synonyms	3-Cyano-2-amino-7,7-dimethyl-4-(3-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene; 4H-Chromene-3-carbonitrile, 2-amino-7,7-dimethyl-4-(3-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-; 2-Amino-4-(3-nitrophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; Tetrahydrochromene Carbonitrile Derivative; 3-Nitrophenyl Substituted Chromene Nitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-7,7-Dimethyl-4-(3-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.