Description

2-Amino-7,7-Dimethyl-4-(4-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value, multifunctional heterocyclic organic compound with a complex chromene scaffold. This molecule is of significant commercial interest due to its role as a versatile synthetic intermediate and a core structural motif in active pharmaceutical ingredient (API) development. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for the synthesis of novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and microbial infections.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its complex heterocyclic structure for bioactivity.
• Organic Synthesis & Catalysis: Acts as a precursor for creating complex molecular libraries for high-throughput screening (HTS) in drug discovery programs.
• Material Science Research: Investigated for the development of organic semiconductors, nonlinear optical (NLO) materials, and fluorescent dyes due to its conjugated system.
• Academic & R&D: Employed in universities and corporate R&D labs for methodological studies in multicomponent reactions (MCRs) and heterocyclic chemistry.

Basic Information

Product Name	2-Amino-7,7-Dimethyl-4-(4-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	144036-35-1
Molecular Formula	C18H17N3O3
Molecular Weight	323.35 g/mol
Synonyms	4H-Chromene-3-carbonitrile, 2-amino-7,7-dimethyl-4-(4-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-; 2-Amino-4-(4-nitrophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 3-Cyano-2-amino-7,7-dimethyl-4-(4-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene; Tetrahydrochromene carbonitrile derivative; Knoevenagel condensation product
EINECS	Contact for details

Quality Control

Our 2-Amino-7,7-Dimethyl-4-(4-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for research and development and GMP-grade intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.