Description

2-Amino-4-(2,4-Dichlorophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex chromene-based molecular structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides due to its bioactive heterocyclic core.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing complex molecular libraries in medicinal and combinatorial chemistry.
• Academic & Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Utilized in the manufacture of specialty dyes, pigments, and other performance chemicals where its specific chromophore structure is advantageous.

Basic Information

Product Name	2-Amino-4-(2,4-Dichlorophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	144036-33-9
Molecular Formula	C18H16Cl2N2O2
Molecular Weight	363.24 g/mol
Synonyms	2-Amino-4-(2,4-dichlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(2,4-dichlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-; 2-Amino-4-(2,4-dichlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyran-3-carbonitrile; Chromene-3-carbonitrile derivative (CAS 144036-33-9); 2-Amino-4-(2,4-dichlorophenyl)-7,7-dimethyl-5-oxotetrahydro-4H-chromene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(2,4-Dichlorophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.