Description

3-Furancarboxylicacid,Tetrahydro-3-Hydroxy-5-Oxo-,Methylester,(S)-(9Ci) is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and fine chemicals where stereochemical control is paramount. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring a tetrahydrofuran moiety with defined stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that leverage its unique furan-based structure.
• Fine Chemical Production: Serves as a versatile precursor for flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent in methodological development for asymmetric synthesis and natural product total synthesis.
• Ligand and Catalyst Development: Potential use in the preparation of chiral ligands or organocatalysts for enantioselective transformations.

Basic Information

Product Name	3-Furancarboxylicacid,Tetrahydro-3-Hydroxy-5-Oxo-,Methylester,(S)-(9Ci)
CAS No.	143858-30-4
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	(S)-Methyl 3-hydroxy-5-oxotetrahydrofuran-3-carboxylate; Methyl (3S)-3-hydroxy-5-oxooxolane-3-carboxylate; (S)-3-Hydroxy-5-oxotetrahydrofuran-3-carboxylic acid methyl ester; Tetrahydro-3-hydroxy-5-oxo-3-furancarboxylic acid methyl ester, (S)-; 143858-30-4; (S)-Methyl 3-hydroxy-5-oxodihydrofuran-3-carboxylate; (3S)-3-Hydroxy-5-oxotetrahydrofuran-3-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 3-Furancarboxylicacid,Tetrahydro-3-Hydroxy-5-Oxo-,Methylester,(S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting customer specifications and industry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.