Description

1-Aminomethyl-Cyclopropylamine is a versatile bifunctional amine featuring both a primary amine and a cyclopropylamine group, making it a valuable building block in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its rigid cyclopropane ring can impart unique biological activity and metabolic stability. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production require this high-purity intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug candidates targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, where the cyclopropyl moiety enhances compound stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and metal-organic catalysts used in asymmetric synthesis.
• Polymer Modification: Employed as a cross-linking agent or curing agent in the production of specialty polymers, resins, and epoxy systems to improve thermal and mechanical properties.
• Research & Development: Essential for medicinal chemistry and process chemistry research in academic and industrial laboratories for exploring new chemical entities.
• Fine Chemical Production: Acts as a key intermediate in the multi-step synthesis of complex fine chemicals and dyes.

Basic Information

Item	Details
Product Name	1-Aminomethyl-Cyclopropylamine
CAS No.	143842-25-5
Molecular Formula	C4H10N2
Molecular Weight	86.14 g/mol
Synonyms	(Aminomethyl)cyclopropylamine; Cyclopropanemethylamine, 1-amino-; 1-Cyclopropyl-1,2-ethanediamine; 1-Amino-1-cyclopropylmethanamine; 1-(Aminomethyl)cyclopropanamine; CPMA; Aminomethylcyclopropylamine
EINECS	Contact for details

Quality Control

Our 1-Aminomethyl-Cyclopropylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and a strong base; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation and moisture absorption. Keep away from heat, sparks, and incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	0.92 - 0.96

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.