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(5-Bromothiophen-2-Yl)Tributylstannane CAS NO 143724-36-1
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CAS No.:143724-36-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(5-Bromothiophen-2-Yl)Tributylstannane is a high-purity organotin reagent, specifically a tributylstannyl derivative of 5-bromothiophene. This compound is a critical building block in modern organic synthesis, enabling efficient carbon-carbon bond formation via Stille cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex heterocyclic molecules.
Application
- Pharmaceutical Intermediate Synthesis: A key reagent for the Stille coupling-based construction of complex thiophene-containing drug candidates, including kinase inhibitors and antiviral agents.
- Agrochemical Development: Used in the synthesis of novel active ingredients that incorporate the 5-bromothiophene moiety for crop protection products.
- Organic Electronics & Materials Science: Serves as a precursor for synthesizing conjugated polymers and small molecules for use in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
- Chemical Research & Development: An essential tool for academic and industrial R&D labs exploring new synthetic methodologies and constructing diverse thiophene-based molecular libraries.
- Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts where the thiophene unit is a core structural element.
Basic Information
| Product Name | (5-Bromothiophen-2-Yl)Tributylstannane |
| CAS No. | 143724-36-1 |
| Molecular Formula | C16H29BrSSn |
| Molecular Weight | 452.06 g/mol |
| Synonyms | 5-Bromo-2-(tributylstannyl)thiophene; Tributyl(5-bromothiophen-2-yl)stannane; 2-(Tributylstannyl)-5-bromothiophene; Stannane, tributyl(5-bromothiophen-2-yl)-; (5-Bromo-2-thienyl)tributylstannane; 5-Bromothiophene-2-tributyltin |
| EINECS | Contact for details |
Quality Control
Our (5-Bromothiophen-2-Yl)Tributylstannane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot is characterized by NMR (1H, 13C), GC or HPLC analysis, and other relevant spectroscopic methods to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C. This material is moisture-sensitive and easily oxidized; ensure containers are sealed properly after each use to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (NMR) | Conforms to structure |
| Purity (GC/HPLC) | ≥ 95% (Typical 97-99%) |
| Tin (Sn) Content | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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