Description

3-(2-Fluorophenyl)Propyl 4-Methylbenzenesulfonate is a high-purity organic synthetic intermediate characterized by its fluorinated aromatic and sulfonate ester functional groups. This compound is valued for its role as a versatile building block in advanced pharmaceutical and agrochemical research, enabling the introduction of specific fluorophenyl motifs into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioisosteres for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the fluorophenyl group can contribute to biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Material Precursor: Serves as a synthetic intermediate for fluorinated aromatic compounds used in electronic materials, such as liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in organic synthesis, including cross-coupling reactions and functional group transformations involving sulfonate esters.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke chemicals and non-commercial quantities for client-specific projects.

Basic Information

Product Name	3-(2-Fluorophenyl)Propyl 4-Methylbenzenesulfonate
CAS No.	143654-60-8
Molecular Formula	C₁₆H₁₇FO₃S
Molecular Weight	308.37 g/mol
Synonyms	3-(2-Fluorophenyl)propyl p-toluenesulfonate; 1-(2-Fluorophenyl)-3-(tosyloxy)propane; 2-Fluorophenylpropyl tosylate; p-Toluenesulfonic acid 3-(2-fluorophenyl)propyl ester; 3-(2-Fluorophenyl)propyl tosylate; Tosylate of 3-(2-fluorophenyl)propan-1-ol
EINECS	Contact for details

Quality Control

Our 3-(2-Fluorophenyl)Propyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.