Description

Carbamic Acid, [(1S)-1-(1-Methylethyl)-2-Propynyl]-, 1,1-Dimethylethyl Ester is a specialized chiral carbamate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine functionality and a stereogenic center, enabling the controlled construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurologic and metabolic disease pathways.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel chiral catalysts for stereoselective reactions.
• Peptidomimetics & PROTACs: A valuable building block for constructing peptide analogs and Proteolysis-Targeting Chimeras (PROTACs) in drug discovery.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with tailored properties.

Basic Information

Product Name	Carbamic Acid, [(1S)-1-(1-Methylethyl)-2-Propynyl]-, 1,1-Dimethylethyl Ester
CAS No.	143327-78-0
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-valinol propargyl ether; tert-Butyl N-[(1S)-1-(1-methylethyl)-2-propynyl]carbamate; (S)-tert-Butyl (1-isopropyl-2-propynyl)carbamate; BOC-L-Valinol propargyl ether; BOC-Valinol propargyl ether; (S)-N-Boc-1-amino-3-methyl-2-butyn-4-ol; Carbamic acid, N-[(1S)-1-(1-methylethyl)-2-propynyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1S)-1-(1-Methylethyl)-2-Propynyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chemical and chiral purity, meeting the exacting standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.