Description

3-(4-Chlorophenyl)-5-(Trifluoromethyl)-1H-Pyrazole is a high-purity, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chlorophenyl and trifluoromethyl substituents, makes it a valuable intermediate for creating molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Active Ingredient Synthesis: Used to construct advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole core and the stability imparted by fluorine.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	3-(4-Chlorophenyl)-5-(Trifluoromethyl)-1H-Pyrazole
CAS No.	142623-90-3
Molecular Formula	C10H6ClF3N2
Molecular Weight	246.62 g/mol
Synonyms	5-(Trifluoromethyl)-3-(4-chlorophenyl)-1H-pyrazole; 3-(p-Chlorophenyl)-5-(trifluoromethyl)pyrazole; 1H-Pyrazole, 3-(4-chlorophenyl)-5-(trifluoromethyl)-; 4-Chloro-α,α,α-trifluoro-3-pyrazol-5-yltoluene; 3-(4-Chlorophenyl)-5-trifluoromethylpyrazole
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Chlorophenyl)-5-(Trifluoromethyl)-1H-Pyrazole is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.