Description

1-(4-(Trifluoromethoxy)Phenyl)-2-Thiourea is a specialized thiourea derivative featuring a trifluoromethoxy phenyl substituent. This compound is a valuable synthetic intermediate and building block in advanced organic synthesis, prized for its unique electronic and steric properties imparted by the fluorine-containing functional group. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for targets requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the trifluoromethoxy group can enhance biological activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile precursor for heterocyclic compounds, including thiazoles and other sulfur-nitrogen containing ring systems.
• Material Science Research: Investigated as a monomer or additive in the creation of specialized polymers and advanced materials with specific electronic properties.
• Chemical Biology Probe: Utilized in research to study enzyme inhibition or as a molecular tag due to its specific chemical reactivity.

Basic Information

Product Name	1-(4-(Trifluoromethoxy)Phenyl)-2-Thiourea
CAS No.	142229-74-1
Molecular Formula	C8H7F3N2OS
Molecular Weight	236.22 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]thiourea; N-[4-(Trifluoromethoxy)phenyl]thiourea; 4-(Trifluoromethoxy)phenylthiourea; p-(Trifluoromethoxy)phenylthiourea; (4-Trifluoromethoxyphenyl)thiourea; Thiourea, N-[4-(trifluoromethoxy)phenyl]-; CAS 142229-74-1
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethoxy)Phenyl)-2-Thiourea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.