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2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution CAS NO 142072-11-5


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CAS No.:142072-11-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution is a key protected glycosyl donor intermediate, specifically designed for advanced carbohydrate synthesis and glycoconjugate chemistry. Its value lies in providing a reactive azidoethyl handle for subsequent "click chemistry" modifications, enabling the precise construction of complex oligosaccharides and glycoconjugates under mild conditions. This high-purity solution is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycan-based therapeutics, vaccines, and diagnostic probes.

Application

  • Glycoconjugate Vaccine Development: Serves as a critical building block for synthesizing carbohydrate antigens to be conjugated to carrier proteins.
  • Oligosaccharide & Polysaccharide Synthesis: Used as a glycosyl donor in automated or solution-phase synthesis of complex, biologically active carbohydrate chains.
  • Chemical Biology & Probe Design: Enables site-specific labeling of biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for imaging and interaction studies.
  • Pharmaceutical Intermediate: A precursor in the synthesis of novel glycosidase inhibitors, antiviral agents, and other carbohydrate-based drugs.
  • Material Science Functionalization: Used to introduce carbohydrate motifs onto surfaces, polymers, or nanoparticles for biocompatibility or targeted delivery applications.
  • Neoglycoconjugate Production: Facilitates the creation of artificial glycoproteins and glycolipids for immunological and biochemical research.

Basic Information

Product Name 2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution
CAS No. 142072-11-5
Molecular Formula C₁₆H₂₄N₄O₁₀
Molecular Weight 432.38 g/mol
Synonyms 2-Azidoethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; 2-Azidoethyl N-Acetyl-β-D-glucosaminide Triacetate; 2-Azidoethyl GlcNAc(β1-)-Triacetate; Azidoethyl-GlcNAc(Ac)₃; Glycosyl Azide Donor; N-Acetylglucosamine Azidoethyl Glycoside; 1,3,4,6-Tetra-O-acetyl-2-azidoethyl-2-deoxy-β-D-glucopyranoside (related protected form); Contact for additional aliases.
EINECS Contact for details

Quality Control

Every batch of our 2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution is manufactured and tested under strict quality management systems. We employ advanced analytical techniques, including HPLC and NMR, to ensure high chemical purity, correct stereochemistry (β-anomer), and consistent solution concentration. A comprehensive Certificate of Analysis (COA) detailing identity, purity, solvent content, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as specified on the label or COA. The solution is sensitive to light and moisture; ensure containers are kept sealed under an inert atmosphere if specified. Keep away from strong acids and oxidizing agents. For long-term storage, consider freezing at -20°C under inert atmosphere.

Specification

Item Specification
Appearance Clear, colorless to pale yellow solution
Identification (HPLC/MS) Conforms to reference standard
Identification (NMR) ¹H NMR spectrum conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Anomeric Purity (β-form) ≥ 98%
Solvent Content As specified (e.g., Dichloromethane, Acetonitrile)
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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