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2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution CAS NO 142072-11-5
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CAS No.:142072-11-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution is a key protected glycosyl donor intermediate, specifically designed for advanced carbohydrate synthesis and glycoconjugate chemistry. Its value lies in providing a reactive azidoethyl handle for subsequent "click chemistry" modifications, enabling the precise construction of complex oligosaccharides and glycoconjugates under mild conditions. This high-purity solution is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycan-based therapeutics, vaccines, and diagnostic probes.
Application
- Glycoconjugate Vaccine Development: Serves as a critical building block for synthesizing carbohydrate antigens to be conjugated to carrier proteins.
- Oligosaccharide & Polysaccharide Synthesis: Used as a glycosyl donor in automated or solution-phase synthesis of complex, biologically active carbohydrate chains.
- Chemical Biology & Probe Design: Enables site-specific labeling of biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for imaging and interaction studies.
- Pharmaceutical Intermediate: A precursor in the synthesis of novel glycosidase inhibitors, antiviral agents, and other carbohydrate-based drugs.
- Material Science Functionalization: Used to introduce carbohydrate motifs onto surfaces, polymers, or nanoparticles for biocompatibility or targeted delivery applications.
- Neoglycoconjugate Production: Facilitates the creation of artificial glycoproteins and glycolipids for immunological and biochemical research.
Basic Information
| Product Name | 2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution |
| CAS No. | 142072-11-5 |
| Molecular Formula | C₁₆H₂₄N₄O₁₀ |
| Molecular Weight | 432.38 g/mol |
| Synonyms | 2-Azidoethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; 2-Azidoethyl N-Acetyl-β-D-glucosaminide Triacetate; 2-Azidoethyl GlcNAc(β1-)-Triacetate; Azidoethyl-GlcNAc(Ac)₃; Glycosyl Azide Donor; N-Acetylglucosamine Azidoethyl Glycoside; 1,3,4,6-Tetra-O-acetyl-2-azidoethyl-2-deoxy-β-D-glucopyranoside (related protected form); Contact for additional aliases. |
| EINECS | Contact for details |
Quality Control
Every batch of our 2-Azidoethyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside Solution is manufactured and tested under strict quality management systems. We employ advanced analytical techniques, including HPLC and NMR, to ensure high chemical purity, correct stereochemistry (β-anomer), and consistent solution concentration. A comprehensive Certificate of Analysis (COA) detailing identity, purity, solvent content, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as specified on the label or COA. The solution is sensitive to light and moisture; ensure containers are kept sealed under an inert atmosphere if specified. Keep away from strong acids and oxidizing agents. For long-term storage, consider freezing at -20°C under inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to pale yellow solution |
| Identification (HPLC/MS) | Conforms to reference standard |
| Identification (NMR) | ¹H NMR spectrum conforms to structure |
| Purity (HPLC) | ≥ 95% (Area %) |
| Anomeric Purity (β-form) | ≥ 98% |
| Solvent Content | As specified (e.g., Dichloromethane, Acetonitrile) |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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