Description

3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic Acid Tert Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and oncology. It is primarily sought after by research institutions, custom synthesis laboratories, and large-scale pharmaceutical manufacturers engaged in the development of complex, small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those containing pyrrolidine scaffolds.
• Protease Inhibitor Development: Used in research and production of inhibitors targeting specific enzymes.
• Peptidomimetic Chemistry: Serves as a constrained scaffold for designing peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A vital raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Industrial R&D: Employed in exploratory chemistry for discovering new chemical entities with potential therapeutic value.

Basic Information

Product Name	3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic Acid Tert Butyl Ester
CAS No.	141699-56-1
Molecular Formula	C12H21NO5S
Molecular Weight	291.36 g/mol
Synonyms	1-Boc-3-(methanesulfonyloxymethyl)pyrrolidine; tert-Butyl 3-((methylsulfonyloxy)methyl)pyrrolidine-1-carboxylate; 3-((Methylsulfonyloxy)methyl)-1-(tert-butoxycarbonyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-((methylsulfonyloxy)methyl)pyrrolidine; 3-(Methanesulfonyloxymethyl)pyrrolidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-methanesulfonyloxymethylpyrrolidine; Pyrrolidine-1-carboxylic acid, 3-[(methylsulfonyl)oxy]methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic Acid Tert Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.